Call for papers: Innovations in Enabling Formulations and Characterization of Small Molecules for Drug Development
This special issue focuses on recent theoretical and experimental advances in small molecule formulation development. It highlights innovative strategies to address challenges such as stability, solubility, permeability, and drug disposition. Contributions are invited in areas including biopharmaceutics, preformulation, drug delivery systems, formulation design, and modeling, as well as emerging analytical technologies that offer mechanistic insights. | Submission Deadline: 28 February 2026
Call for papers: Advances in Large Molecule Drug Delivery
This special issue explores the evolving landscape of large molecule drug delivery, focusing on innovative strategies to address the unique challenges of biologics such as proteins, peptides, and nucleic acids. It highlights cutting-edge delivery platforms including nanoparticles, antibody-drug conjugates, and lipid-based carriers, while also emphasizing integrated approaches across formulation, characterization, manufacturing, and device development. | Submission Deadline: 31 January 2026
Call for papers: Artificial Intelligence and Computational Tools in Drug Development
This special issue explores the transformative role of AI in pharmaceutics, from drug discovery and design to optimizing delivery systems and personalized therapies. It highlights AI’s impact on predictive analytics, pharmacokinetics, and pharmacodynamics, enhancing patient outcomes. A key focus is advancing computational tools to simulate drug behavior and improve development processes. The issue also addresses ethical, regulatory, and practical challenges, fostering synergy between AI and pharmaceutical sciences to tackle complex industry challenges. | Submission Deadline: 30 November 2025
Call for papers: Steven L. Nail Dedicated Issue on Freeze Drying Technology: Recent Advances, Innovations and Applications
This special issue aims to highlight the current state-of-the-art and future directions of pharmaceutical drying technologies, including conventional container-based freeze-drying but also encompassing alternate emerging drying technologies such as spray drying, spray freeze drying, microwave freeze-drying, lyospheres or lyobeads, spin freeze-drying, thin film freeze-drying, foam drying and microglassificaton, etc. The Issue also aims to highlight advances in formulations and processing, analytical characterization, equipment considerations, regulatory compliance and industry best practices for the development and manufacturing of dried pharmaceuticals. | Submission Deadline: 31 August 2025
Articles
-
-
Spotlighting rising researcher Mikaela Gray: one ingredient intracellular delivery of RNA by hydrophobic ion pairing
-
Rising Researchers: the AAPS Open Editorial Series of Early Career Pharmaceutical Scientists
-
Optimization and transfer of robust primary drying protocols for biopharmaceuticals through lyophilization process modeling
-
Illuminating innovation: from test tubes to translational triumphs: a personal journey advancing pharmaceutical innovation
-
ANVISA: an introduction to a new regulatory agency with many challenges
-
A review of in vivo and in vitro aspects of alcohol-induced dose dumping
-
Drug manufacturing and access to medicines: the West African story. A literature review of challenges and proposed remediation
-
Solid form changes during drug development: good, bad, and ugly case studies
-
Stability challenges not addressed by harmonized guidance – AAPS workshop of the stability focus group, April 3rd- 4th, 2017 in Rockville, MD
Aims and scope
AAPS Open, an American Association of Pharmaceutical Scientists (AAPS) journal and its flagship open access title, aims to be the first global address for open access publication in the pharmaceutical sciences. AAPS Open is characterized by its rigorous but fast review timelines, breadth of article formats, and a special focus on applied sciences. View full journal scope here.
The AAPS Journals Make Use of Portable Peer Review
If your manuscript has been declined, and you are planning to submit your article to another of the four AAPS journals (AAPS Open, The AAPS Journal, AAPSPharmSciTech, or Pharmaceutical Research), we can help make the peer review process faster and smoother by extending the use of previous peer reviewer comments! Portable Peer Review, an opt-into service available for any author of these journals, allows us to share, between the portfolio, previous peer review comments and reviewer names, subject to approval of all parties. This can help speed up the assessment process, should the editor choose to make a decision on the basis of the comments and revision. Interested? Email us with the name of the journal to which you are going to submit. Note: Portable peer review is opt-in only, available at the authors’ preference, and the reviewer identities and comments will only be shared between offices, not to the author.
Collections open for submissions
Innovations in Enabling Formulations and Characterization of Small Molecules for Drug Development
Edited by Ahmed Elkhabaz, Abu Zayed Md Badruddoza, Deliang Zhou, Yihong Qiu, Dana E. Moseson, and Marina Solomos
Advances in Large Molecule Drug Delivery
Edited by Chun-Wan Yen, Lauren A. Austin, Karthik Rajagopal, Tarik Khan, Chi-An Cheng, and Kurt Ristroph
Artificial Intelligence and Computational Tools in Drug Development
Edited by LR Jaidev Chakka, Yu Catherine Zhang, and Mo Maniruzzaman
Freeze Drying Technology: Recent Advances, Innovations and Applications
Edited by Shreya Kulkarni, Harshil Renawala, Alina Alexeenko, Akhilesh Bhambhani, Bakul Bhatnagar, Robin Bogner, and Xiuling Lu
Editorial Collections
Rising Researchers: Profiles of Early Career Pharmaceutical Scientists
Edited by Dana Moseson-Tarrh
Illuminating Innovation: Profiles of AAPS Fellows and Awardees
Edited by Yongchao Su, Patrick Ronaldson, and M.N.V. Ravi Kumar
Editor Announcements
Click below to read updates about AAPS Open's editorial board!
Read MoreSociety affiliation
AAPS Open is an official journal of the American Association of Pharmaceutical Scientists.
Latest Tweets
View Twitter timeline
Your browser needs to have JavaScript enabled to view this timeline
Follow
Affiliated with
Annual Journal Metrics
-
Speed
Submission to first editorial decision (median days): 16
Submission to acceptance (median days): 114Usage 2024
Downloads: 131,494
Altmetric mentions: 11
- ISSN: 2364-9534 (electronic)